Variation in fine-scale genetic structure and local dispersal patterns between peripheral populations of a South American passerine bird

Indexación: Scopus.The distribution of suitable habitat influences natal and breeding dispersal at small spatial scales, resulting in strong microgeographic genetic structure. Although environmental variation can promote interpopulation differences in dispersal behavior and local spatial patterns, the effects of distinct ecological conditions on within-species variation in dispersal strategies and in fine-scale genetic structure remain poorly understood. We studied local dispersal and fine-scale genetic structure in the thorn-tailed rayadito (Aphrastura spinicauda), a South American bird that breeds along a wide latitudinal gradient. We combine capture-mark-recapture data from eight breeding seasons and molecular genetics to compare two peripheral populations with contrasting environments in Chile: Navarino Island, a continuous and low density habitat, and Fray Jorge National Park, a fragmented, densely populated and more stressful environment. Natal dispersal showed no sex bias in Navarino but was female-biased in the more dense population in Fray Jorge. In the latter, male movements were restricted, and some birds seemed to skip breeding in their first year, suggesting habitat saturation. Breeding dispersal was limited in both populations, with males being more philopatric than females. Spatial genetic autocorrelation analyzes using 13 polymorphic microsatellite loci confirmed the observed dispersal patterns: a fine-scale genetic structure was only detectable for males in Fray Jorge for distances up to 450 m. Furthermore, two-dimensional autocorrelation analyzes and estimates of genetic relatedness indicated that related males tended to be spatially clustered in this population. Our study shows evidence for context-dependent variation in natal dispersal and corresponding local genetic structure in peripheral populations of this bird. It seems likely that the costs of dispersal are higher in the fragmented and higher density environment in Fray Jorge, particularly for males. The observed differences in microgeographic genetic structure for rayaditos might reflect the genetic consequences of population-specific responses to contrasting environmental pressures near the range limits of its distribution.http://onlinelibrary.wiley.com/doi/10.1002/ece3.3342/epd

The G\=oMartini approach: Revisiting the concept of contact maps and the modelling of protein complexes

We present a review of a series of contact maps for the determination of native interactions in proteins and nucleic acids based on a distance-threshold. Such contact maps are mostly based on physical and chemical construction, and yet they are sensitive to some parameters (e.g. distances or atomic radii) and can neglect some key interactions. Furthermore, we also comment on a new class of contact maps that only requires geometric arguments. The contact map is a necessary ingredient to build a robust G\=oMartini model for proteins and their complexes in the Martini 3 force field. We present the extension of a popular structure-based G\=o-like approach for the study of protein-sugar complexes, and also limitations of this approach are discussed. The G\=oMartini approach was first introduced by Poma et al. J. Chem. Theory Comput. 2017, 13(3), 1366-1374 in Martini 2 force field and recently, it has gained the status of gold-standard for protein simulation undergoing conformational changes in Martini 3 force field. We discuss several studies that have provided support to this approach in the context of the biophysical community.Comment: 19 pages, 3 figure

Response of Growing Dairy Bulls to Dietary Tannin in Rations with Varying Energy Levels

This study was conducted to determine the effect of dietary tannin on growth performance, rumen fluid characteristics, and apparent total-tract digestibility in growing Holstein-Friesian x Sahiwal bulls fed low and high energy rations. Eighteen growing bulls with initial body weight (BW) of 162.8±12.7 kg at 15±0.80 months were used in an unbalanced randomized complete block design set-up in a 2x2 factorial arrangement. The experimental animals were blocked by their respective BW. Animals were fed with concentrates containing metabolizable energy (ME) at 2.47 and 2.72 Mcal/kg without or with 20g/kg tannin in dry matter basis. At the final week of the trial, rumen fluid and fecal samples were collected for the rumen fluid characteristics and apparent total-tract digestibility analyses. No differences (p>0.05) were observed between the growth performance, rumen gas production, volatile fatty acids as well as organic matter, crude protein, and energy digestibility. High energy concentrates had higher (p<0.05) dry matter and neutral detergent fiber digestibility than low energy concentrates. Low energy concentrates without tannin had cheaper (p<0.001) total feed cost but feed cost per kilogram BW gain was similar (p>0.05) across treatments. Feed savings costs of US$ 17.58 per animal were attained in feeding low energy concentrates without tannin. Therefore, feeding concentrates containing 2.47 Mcal/kg ME without additional tannin can still be fed economically to growing cattle without any adverse effect on growth, ruminal fermentation characteristics, and apparent total-tract digestibility

Effectively Including Human Factors in the Design of New Facilities

Human error is a major cause of incidents in the offshore industry. For example, in the Gulf of Mexico region in 1998, 38% of all incidents were attributed to human error with an additional 9% of incidents resulting from slips, trips, and falls (MMS 2000-021, OCS Report). Human Factors, when integrated during the design of a new offshore facility, can reduce the potential for human error and the occurrence of unfortunate incidents. Quite often the implementation of Human Factors (HF) during design is disregarded because of the notion that it will add unacceptable costs. Review of the cost/benefit data contained in this paper proves that notion to be untrue. Although cost/benefit is important, it was not the primary focus of this Working Group. This paper’s focus is to develop a means or a strategy to effectively integrate the application of HF design principles into all phases of a new capital design project. This Working Group’s objective during the Second International Workshop on Human Factors in Offshore Operations was to generate discussion concerning HF integration strategies and to focus on specific implementation issues that have been shown to be successful. These include but are not limited to: · The factors critical to the success of HF integration · What HF activities should be conducted · At what stage during the various design phases should HF activities take place · HF strategies, how to decide what level of human factors engineering is required · The qualifications and responsibilities of those executing HF activitie

Effectively Including Human Factors in the Design of New Facilities

Human error is a major cause of incidents in the offshore industry. For example, in the Gulf of Mexico region in 1998, 38% of all incidents were attributed to human error with an additional 9% of incidents resulting from slips, trips, and falls (MMS 2000-021, OCS Report). Human Factors, when integrated during the design of a new offshore facility, can reduce the potential for human error and the occurrence of unfortunate incidents. Quite often the implementation of Human Factors (HF) during design is disregarded because of the notion that it will add unacceptable costs. Review of the cost/benefit data contained in this paper proves that notion to be untrue. Although cost/benefit is important, it was not the primary focus of this Working Group. This paper’s focus is to develop a means or a strategy to effectively integrate the application of HF design principles into all phases of a new capital design project. This Working Group’s objective during the Second International Workshop on Human Factors in Offshore Operations was to generate discussion concerning HF integration strategies and to focus on specific implementation issues that have been shown to be successful. These include but are not limited to: · The factors critical to the success of HF integration · What HF activities should be conducted · At what stage during the various design phases should HF activities take place · HF strategies, how to decide what level of human factors engineering is required · The qualifications and responsibilities of those executing HF activitie

Global scenarios of residential heating and cooling energy demand and CO2 emissions

Buildings account for 36% of global final energy demand and are key to mitigating climate change. Assessing the evolution of the global building stock and its energy demand is critical to support mitigation strategies. However, most global studies lack granularity and overlook heterogeneity in the building sector, limiting the evaluation of demand transformation scenarios. We develop global residential building scenarios along the shared socio-economic pathways (SSPs) 1–3 and assess the evolution of building stock, energy demand, and CO2 emissions for space heating and cooling with MESSAGEix-Buildings, a modelling framework soft-linked to an integrated assessment framework. MESSAGEix-Buildings combines bottom-up modelling of energy demand, stock turnover, and discrete choice modelling for energy efficiency decisions, and accounts for heterogeneity in geographical contexts, socio-economics, and buildings characteristics. Global CO2 emissions for space heating are projected to decrease between 34.4 (SSP3) and 52.5% (SSP1) by 2050 under energy efficiency improvements and electrification. Space cooling demand starkly rises in developing countries, with CO2 emissions increasing globally by 58.2 (SSP1) to 85.2% (SSP3) by 2050. Scenarios substantially differ in the uptake of energy efficient new construction and renovations, generally higher for single-family homes, and in space cooling patterns across income levels and locations, with most of the demand in the global south driven by medium- and high-income urban households. This study contributes an advancement in the granularity of building sector knowledge to be assessed in integration with other sources of emissions in the context of global climate change mitigation and sustainable development

Prevalence Rates of Mental Disorders in Chilean Prisons

PMCID: PMC371883

Integrating energy access, efficiency and renewable energy policies in Sub-Saharan Africa: a model-based analysis

The role of energy in social and economic development is recognised by sustainable development goal 7 that targets three aspects of energy access: ensure universal access to affordable, reliable and modern energy services, substantially increase the share of renewable energy, and double the global rate of improvement in energy efficiency. With the projected increase in population, income and energy access in Sub-Saharan Africa, demand for energy services is expected to increase. This increase can be met through increasing the supply while at the same time improving households' energy efficiency. In this paper, we explore the interactions between the three SDG7 targets by applying two Integrated Assessment Models, IMAGE and MESSAGE, that incorporate socio-economic heterogeneity of the end-user. The results of the study depict the synergistic relationships between the three SDG7 objectives. Relative to pursuing only the universal access target, integration of all three targets could i) reduce residential final energy consumption by up to 25%, enabling the use of mini-grid and stand-alone systems to provide better energy services, ii) cut annual energy-use-related residential emissions by a third, and iii) lower energy related investments by up to 30% to save scarce finance

Divergent abiotic spectral pathways unravel pathogen stress signals across species

Abstract: Plant pathogens pose increasing threats to global food security, causing yield losses that exceed 30% in food-deficit regions. Xylella fastidiosa (Xf) represents the major transboundary plant pest and one of the world’s most damaging pathogens in terms of socioeconomic impact. Spectral screening methods are critical to detect non-visual symptoms of early infection and prevent spread. However, the subtle pathogen-induced physiological alterations that are spectrally detectable are entangled with the dynamics of abiotic stresses. Here, using airborne spectroscopy and thermal scanning of areas covering more than one million trees of different species, infections and water stress levels, we reveal the existence of divergent pathogen- and host-specific spectral pathways that can disentangle biotic-induced symptoms. We demonstrate that uncoupling this biotic–abiotic spectral dynamics diminishes the uncertainty in the Xf detection to below 6% across different hosts. Assessing these deviating pathways against another harmful vascular pathogen that produces analogous symptoms, Verticillium dahliae, the divergent routes remained pathogen- and host-specific, revealing detection accuracies exceeding 92% across pathosystems. These urgently needed hyperspectral methods advance early detection of devastating pathogens to reduce the billions in crop losses worldwide

Limited life cycle and cost assessment for the bioconversion of lignin-derived aromatics into adipic acid

Lignin is an abundant and heterogeneous waste byproduct of the cellulosic industry, which has the potential of being transformed into valuable biochemicals via microbial fermentation. In this study, we applied a fast-pyrolysis process using softwood lignin resulting in a two-phase bio-oil containing monomeric and oligomeric aromatics without syringol. We demonstrated that an additional hydrodeoxygenation step within the process leads to an enhanced thermochemical conversion of guaiacol into catechol and phenol. After steam bath distillation, Pseudomonas putida KT2440-BN6 achieved a percent yield of cis, cis-muconic acid of up to 95 mol% from catechol derived from the aqueous phase. We next established a downstream process for purifying cis, cis-muconic acid (39.9 g/L) produced in a 42.5 L fermenter using glucose and benzoate as carbon substrates. On the basis of the obtained values for each unit operation of the empirical processes, we next performed a limited life cycle and cost analysis of an integrated biotechnological and chemical process for producing adipic acid and then compared it with the conventional petrochemical route. The simulated scenarios estimate that by attaining a mixture of catechol, phenol, cresol, and guaiacol (1:0.34:0.18:0, mol ratio), a titer of 62.5 (g/L) cis, cis-muconic acid in the bioreactor, and a controlled cooling of pyrolysis gases to concentrate monomeric aromatics in the aqueous phase, the bio-based route results in a reduction of CO2 -eq emission by 58% and energy demand by 23% with a contribution margin for the aqueous phase of up to 88.05 euro/ton. We conclude that the bio-based production of adipic acid from softwood lignins brings environmental benefits over the petrochemical procedure and is cost-effective at an industrial scale. Further research is essential to achieve the proposed cis, cis-muconic acid yield from true lignin-derived aromatics using whole-cell biocatalysts